Friday, May 29, 2020

USING ASPIRIN FOR PROPHYLAXIS AND TREATMENT OF ACUTE MIGRAINES.

Biglione B, Gitin A, Gorelick PB, et al.  Aspirin in the treatment and prevention of migraine headaches: possible additional options for primary healthcare providers.  Review.  Am J Med 2020; 133: 412-416.

Abstract: High dose aspirin from 900-1300 mg at onset of headache  is a safe, effective, available , affordable treatment alternative for acute headache.  Daily aspirin from 82-325 mg daily, is a safe, effective, available , affordable treatment alternative for prophylaxis of headaches.  

The data is drawn from evidence including randomized trials and meta-analyses and showed comparative efficacy to sumatriptan 50 mg. ASA  reduces the frequently concomitant symptoms of nausea, photophonia and phonophobia.