1. oral donepezil is not affected by food, unlike rivastigmine and galanthamine
2. donepezil has 3-5 hours to peak onnset v. 0.5-1 for galanthamine and rivastigmine (oral) and 8-10 hours for rivastigmine patch
3. serum half life is 70-80 hours for oral donepezil, 5-7 hours for galantamine, 2-8 hours for oral rivastigmine, 3-4 hours for rivastigmine patch and 60-80 hours for memantine
